Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Explore the connections between the world of neuroscience and nuances of substance use disorders with our inaugural episode of In Such a Place. We’ll speak with Dr. Anna Radke, a leading expert in the ...

Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in ...

This week, we are reporting on some promising treatments for two of the deadliest drugs in America: opioids and alcohol. William Brangham sat down with one of the nation’s leading researchers who is ...

Matt Field receives research funding from the Medical Research Council, National Institute for Health Research, Alcohol Change UK, and the Academic Forum for the Study of Gambling. He is a trustee of ...

For decades, Americans have been told a simple story about addiction: taking drugs damages the brain—and the earlier in life children start using substances, the more likely they are to progress ...

As weight-loss drugs like Ozempic revolutionize weight loss, scientists hope they may also be life-changing for alcohol addiction. The drugs are one of several approaches doctors and psychiatrists ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

How political red tape and a drug company’s thirst for profits limited the reach of a drug that experts believe could have reduced the opioid epidemic’s toll. Credit...Photo illustration by Ben Denzer ...