From the "pot-bellied" appearance to the flaws in the LDDST, Cushing's disease remains one of our most complex endocrine ...

Crinetics Pharma (($CRNX)) announced an update on their ongoing clinical study. Crinetics Pharmaceuticals is conducting a study titled ‘A Phase ...

This guide helps you better understand Cushing's Syndrome, highlighting its symptoms, causes, and available treatment options ...

Cushing's syndrome and its pituitary variant, Cushing's disease, represent complex endocrine disorders characterised by chronic excessive glucocorticoid exposure. This hypercortisolaemia may be the ...

Expert Rev Endocrinol Metab. 2013;8(2):183-193. Mitotane reduces cortisol synthesis through the inhibition of 11B-hydroxylase, 18-hydroxylase, 3-α hydroxylase, hydroxysteroid dehydrogenase and several ...

WHEN Hannah Richards developed a “moon face” and “buffalo bump” on her back she blamed too many restaurant date nights with her new boyfriend. But after a work colleague ...

ORLANDO, Florida — The investigational drug osilodrostat (Novartis) is showing promise for the treatment of Cushing's disease. Osilodrostat is an orally active inhibitor of 11ß-hydroxylase, the enzyme ...

I have a beloved 14-year-old miniature dachshund that has been tentatively diagnosed with Cushing's disease. I say "tentatively" because we are trying a special food from her vet prior to further ...

Feeling fear is an evolutionary survival tactic. A small number of people have a rare condition that means they're not scared ...

The FDA has approved Novartis’ drug, Isturisa, an oral tablet designed to treat Cushing’s disease. Cushing’s disease is a rare disease caused by a pituitary tumor that causes the adrenal gland to ...